Clinical depression is widely thought to involve problems with two chemicals: serotonin and norepinephrine (also called noradrenaline). When these neurotransmitters don’t go to the right place in your brain, it affects your moods. Common antidepressants — such as selective serotonin reuptake inhibitors — work by redirecting the chemicals.

However, recent research from Spain suggests another kind of medication might help. ScienceDaily reports a study that found people with depression had bad adrenoceptors in their brains that didn’t direct neurotransmitters properly. By using drugs to fix the adrenoceptors, pharmacologist and biochemist Jorge Emilio Ortega Calvo says, doctors hope they can improve treatment for depression by making it more specific to the individual.

While praising SSRIs, Dr. Ronald Duman of Yale University told the Chicago Tribune that individualized treatments are also needed and will likely be more common in the future.